Multicomponent biomarker

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A multicomponent biomarker is a group of biological markers tested together to provide a comprehensive assessment of health, e.g., a lipid panel (blood test) that measures total cholesterol, LDL, HDL, and triglycerides. These four entities would occupy four rows with the component_index from 1 to 4.

Multicomponent single-entity biomarker

biomarker_index component_index entity_index assessed_biomarker_entity
1 1 1 total cholesterol
1 2 1 LDL
1 3 1 HDL
1 4 1 triglycerides

See also AN6165-1.

Multicomponent multi-entity biomarker

biomarker_index component_index entity_index assessed_biomarker_entity
1 1 1 glycan A
1 1 2 protein X
1 2 1 some DNA
1 3 1 some RNA

In this example, component 1 is a glycoprotein, component 2 is a DNA molecule, and component 3 is an RNA molecule.