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	<id>https://wiki.biomarkerkb.org/index.php?action=history&amp;feed=atom&amp;title=Biomarker_Modifications_Terms_Controlled_Vocabulary</id>
	<title>Biomarker Modifications Terms Controlled Vocabulary - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://wiki.biomarkerkb.org/index.php?action=history&amp;feed=atom&amp;title=Biomarker_Modifications_Terms_Controlled_Vocabulary"/>
	<link rel="alternate" type="text/html" href="https://wiki.biomarkerkb.org/index.php?title=Biomarker_Modifications_Terms_Controlled_Vocabulary&amp;action=history"/>
	<updated>2026-05-08T14:16:06Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.42.3</generator>
	<entry>
		<id>https://wiki.biomarkerkb.org/index.php?title=Biomarker_Modifications_Terms_Controlled_Vocabulary&amp;diff=142&amp;oldid=prev</id>
		<title>DaniallMasood at 15:53, 10 December 2025</title>
		<link rel="alternate" type="text/html" href="https://wiki.biomarkerkb.org/index.php?title=Biomarker_Modifications_Terms_Controlled_Vocabulary&amp;diff=142&amp;oldid=prev"/>
		<updated>2025-12-10T15:53:05Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:53, 10 December 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Biomarker Entity Types Controlled Vocabulary]]&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Biomarker Reporting Terms Controlled Vocabulary]]&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Biomarker Aspect Terms Controlled Vocabulary]]&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>DaniallMasood</name></author>
	</entry>
	<entry>
		<id>https://wiki.biomarkerkb.org/index.php?title=Biomarker_Modifications_Terms_Controlled_Vocabulary&amp;diff=122&amp;oldid=prev</id>
		<title>DaniallMasood: new modifications controlled vocab page</title>
		<link rel="alternate" type="text/html" href="https://wiki.biomarkerkb.org/index.php?title=Biomarker_Modifications_Terms_Controlled_Vocabulary&amp;diff=122&amp;oldid=prev"/>
		<updated>2025-11-06T19:28:37Z</updated>

		<summary type="html">&lt;p&gt;new modifications controlled vocab page&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
       BiomarkerKB Controlled Vocabulary:&lt;br /&gt;
&lt;br /&gt;
         Biomarker Modifications Controlled Vocabulary File&lt;br /&gt;
&lt;br /&gt;
         Biomarker Knowledgebase Project&lt;br /&gt;
&lt;br /&gt;
&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Description: Controlled vocabulary of molecular modifications representing&lt;br /&gt;
&lt;br /&gt;
chemical or post-translational changes to biomarker entities.&lt;br /&gt;
&lt;br /&gt;
Name:        modifications.txt&lt;br /&gt;
&lt;br /&gt;
Release:     2025_07_16&lt;br /&gt;
&lt;br /&gt;
&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
 This document lists controlled modification terms that describe chemical,&lt;br /&gt;
&lt;br /&gt;
 structural, or enzymatic alterations to biomarker entities. These terms&lt;br /&gt;
&lt;br /&gt;
 are used to represent states such as methylation, phosphorylation, or&lt;br /&gt;
&lt;br /&gt;
 glycosylation, enabling consistent annotation of modified biomarker forms.&lt;br /&gt;
&lt;br /&gt;
 Each entry consists of the following line codes:&lt;br /&gt;
&lt;br /&gt;
   ----  ----------  ---------------------------  ---------------------------------&lt;br /&gt;
&lt;br /&gt;
 Code  Name        Content                      Occurrences&lt;br /&gt;
&lt;br /&gt;
 ----  ----------  ---------------------------  ---------------------------------&lt;br /&gt;
&lt;br /&gt;
 ID    Identifier      Modification term            Once; starts an entry&lt;br /&gt;
&lt;br /&gt;
 AC   Accession   Unique identifier (MO-xxxx)  Once&lt;br /&gt;
&lt;br /&gt;
 DE   Definition     Definition/description      Once; line wrapping possible&lt;br /&gt;
&lt;br /&gt;
 HI    Hierarchy                                             Optional; zero or more&lt;br /&gt;
&lt;br /&gt;
 EQ   Equivalent   External identifier with     Optional; zero or more&lt;br /&gt;
&lt;br /&gt;
                              same meaning&lt;br /&gt;
&lt;br /&gt;
 EX    Example                                              Optional; zero or once&lt;br /&gt;
&lt;br /&gt;
 NT    Notes                                                   Optional; zero or once; line&lt;br /&gt;
&lt;br /&gt;
                                                                       wrapping possible&lt;br /&gt;
&lt;br /&gt;
 //    Terminator  End of entry                         Once; ends an entry&lt;br /&gt;
&lt;br /&gt;
&amp;lt;nowiki&amp;gt;---------------------------------------------------------------------------&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
ID   methylation&lt;br /&gt;
&lt;br /&gt;
AC   MO-0001&lt;br /&gt;
&lt;br /&gt;
DE   The process in which a methyl group is covalently attached to a molecule.&lt;br /&gt;
&lt;br /&gt;
HI   chemical modification&lt;br /&gt;
&lt;br /&gt;
EQ   GO:0032259; methylation&lt;br /&gt;
&lt;br /&gt;
EX   presence of methylation in DCC; &amp;lt;nowiki&amp;gt;https://biomarkerkb.org/canonical/AN6479&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
//&lt;br /&gt;
&lt;br /&gt;
ID   phosphorylation&lt;br /&gt;
&lt;br /&gt;
AC   MO-0002&lt;br /&gt;
&lt;br /&gt;
DE   The process of introducing a phosphate group into a molecule, usually &lt;br /&gt;
&lt;br /&gt;
DE   with the formation of a phosphoric ester, a phosphoric anhydride or a &lt;br /&gt;
&lt;br /&gt;
DE   phosphoric amide.&lt;br /&gt;
&lt;br /&gt;
HI   post-translational modification&lt;br /&gt;
&lt;br /&gt;
EQ   GO:0016310; phosphorylation&lt;br /&gt;
&lt;br /&gt;
EX   AKT1 S473 Phosphorylation; &amp;lt;nowiki&amp;gt;https://biomarkerkb.org/canonical/AN4659&amp;lt;/nowiki&amp;gt;&lt;br /&gt;
&lt;br /&gt;
//&lt;br /&gt;
&lt;br /&gt;
ID   acetylation&lt;br /&gt;
&lt;br /&gt;
AC   MO-0003&lt;br /&gt;
&lt;br /&gt;
DE   Acetylation involves the covalent linkage of an acetyl group into an &lt;br /&gt;
&lt;br /&gt;
DE   organic molecule.&lt;br /&gt;
&lt;br /&gt;
HI   post-translational modification&lt;br /&gt;
&lt;br /&gt;
EQ   NCIT:C16255; Acetylation&lt;br /&gt;
&lt;br /&gt;
//&lt;br /&gt;
&lt;br /&gt;
ID   glycosylation&lt;br /&gt;
&lt;br /&gt;
AC   MO-0004&lt;br /&gt;
&lt;br /&gt;
DE   The covalent chemical or biochemical addition of carbohydrate or glycosyl &lt;br /&gt;
&lt;br /&gt;
DE   groups to other chemicals, by glycosyl transferases.&lt;br /&gt;
&lt;br /&gt;
HI   post-translational modification&lt;br /&gt;
&lt;br /&gt;
EQ   NCIT:C21034; Glycosylation&lt;br /&gt;
&lt;br /&gt;
//&lt;/div&gt;</summary>
		<author><name>DaniallMasood</name></author>
	</entry>
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