Biomarker Aspect Terms Controlled Vocabulary

Biomarker Entity Types Controlled Vocabulary

Biomarker Reporting Terms Controlled Vocabulary

Biomarker Modifications Terms Controlled Vocabulary

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       BiomarkerKB Controlled Vocabulary:

         Biomarker Aspect Controlled Vocabulary File

         Biomarker Knowledgebase Project

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Description: Controlled vocabulary of standardized aspects used to describe

the specific measurable or biological feature of a biomarker entity.

Name:        aspect.txt

Release:     2025_07_16

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 This document lists controlled terms that represent measurable or

 definable aspects of a biomarker entity. These terms indicate what

 property, modification, or characteristic of the biomarker is being

 evaluated, enabling structured representation of natural language

 phrases such as "increased IL6 level" or "presence of BRCA2 mutation".

 Each entry consists of the following line codes:

   ----  ----------  ---------------------------  ---------------------------------

 Code  Name        Content                      Occurrences

 ----  ----------  ---------------------------  ---------------------------------

 ID    Identifier  Aspect term                  Once; starts an entry

 AC   Accession   Unique identifier (AS-xxxx)  Once

 DE   Definition  Definition/description       Once; line wrapping possible

 HI    Hierarchy                                Optional; zero or more

 EQ    Equivalent  External identifier with     Optional; zero or more

                      same meaning

 EX    Example                                  Optional; zero or once

 NT    Notes                                    Optional; zero or once; line

                                                  wrapping possible

 //    Terminator  End of entry                 Once; ends an entry

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ID   level

AC   AS-0001

DE   A position on a scale measuring intensity, quality, or amount.

EQ   NCIT:C25554; Level

EX   increased IL6 level; https://biomarkerkb.org/canonical/AN6278

//

ID   expression

AC   AS-0002

DE   Production level or transcriptional activity of a gene or RNA molecule.

EQ   GO:0010467; gene expression

EX   differential expression of TNMD; https://biomarkerkb.org/canonical/BB1486

//

ID   mutation

AC   AS-0003

DE   A change in a sequence or structure in comparison to a reference entity

DE   due to an insertion, deletion or substitution event.

DE   within a biomarker entity.

EQ   MI:0118; mutation

EX   presence of rs11571833 mutation in BRCA2;

EX   https://biomarkerkb.org/biomarker/AN7363-3

//